Randy Quaid

Eddie Johnson

Miriam Flynn

Catherine Johnson

Dana Barron

Audrey Griswold

Jake Thomas

Third Johnson

Sung-Hi Lee

Muka Laka Miki

Julian Stone

Melbourne Jack

Beverly Garland

Aunt Jessica

Stephen Furst

Hospital Doctor

Rodger Bumpass

Lab Visitor / Plumber (voice) / Air Controller (voice)

Eric Idle

English Victim

Fred Willard

Professor Doornitz

Ed Asner

Uncle Nick

Kate Simmons

Paige

Maya Quin

Airplane Hostess

Angela Bennett

Doornitz's Assistant

Sal Catalano

Taxi Driver

Jay Greenberg

Santa Claus Security Guard

Trish Suhr

Woman (Next to Nick on Plane)

Cassidy Laikin

Girl in Airport

Caroline Walker

Controller's Wife

Bill Power

Air Traffic Controller